About the Study
The Epidemiology of Diabetes Interventions and Complications (EDIC)
EDIC is a multi-center, longitudinal, observational study designed to utilize the well- characterized Diabetes Control and Complications Trial (DCCT) cohort of 1297 patients. The primary goal of the EDIC study is to determine the long-term effects of prior DCCT treatment assignment on diabetes complications, based on an intention-to-treat analysis. Data collection focuses on nephropathy and macrovascular complications. Annual or biennial measurements (using DCCT methods, standardized protocols and central laboratories) of vascular events, albumin excretion, GFR, ECG, ankle-brachial BP index, serum lipids and HbA1c allows the following analyses: 1) continuation of intention-to-treat analyses to determine long-term effects of prior separation of glycemic levels; 2) risk factors for macrovascular outcomes; 3) correlation of progression of micro- and macrovascular outcomes. The current updated version of the EDIC Protocol is available for download.
More information about the DCCT study is available.