About the Study

The Epidemiology of Diabetes Interventions and Complications (EDIC)

EDIC is a multi-center, longitudinal, observational study designed to utilize the well- characterized Diabetes Control and Complications Trial (DCCT) cohort of 1297 patients. The primary goal of the EDIC study is to determine the long-term effects of prior DCCT treatment assignment on diabetes complications, based on an intention-to-treat analysis. Data collection focuses on nephropathy and macrovascular complications. Annual or biennial measurements (using DCCT methods, standardized protocols and central laboratories) of vascular events, albumin excretion, GFR, ECG, ankle-brachial BP index, serum lipids and HbA1c allows the following analyses: 1) continuation of intention-to-treat analyses to determine long-term effects of prior separation of glycemic levels; 2) risk factors for macrovascular outcomes; 3) correlation of progression of micro- and macrovascular outcomes. The current updated version of the EDIC Protocol is available for download.

More information about the DCCT study is available.

Signed in? Go to EDIC Internal Webpage




Participating Centers

Study Group June 2013



DCCT/EDIC Publications

Google Scholar Page


Collaborating with the EDIC Study

See the attachments below and on the Collaborators page for more information.