DCCT/EDIC Study Published Results: 2010-2019

  • Pop-Busui R, Braffett BH, Zinman B, Martin C, White NH, Herman WH, Genuth S, Gubitosi-Klug R, the DCCT/EDIC Research Group. Cardiovascular Autonomic Neuropathy and Cardiovascular Outcomes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study. Diabetes Care 2017, 40(1):94-100. PMCID:5180458.
  • de Boer IH, Gao X, Cleary PA, Bebu I, Lachin JM, Molitch ME, Orchard T, Paterson AD, Perkins BA, Steffes MW, Zinman B, the DCCT/EDIC Research Group. Albuminuria Changes and Cardiovascular and Renal Outcomes in Type 1 Diabetes: The DCCT/EDIC Study. Clin J Am Soc Nephrol 2016, 11(11):1969-77. PMCID:5108190.
  • Kim C, Karvonen-Gutierrez C, Kong S, Arends V, Steffes M, McConnell DS, Randolph JF Jr, Harlow SD. Antimüllerian hormone among women with and without type 1 diabetes: the Epidemiology of Diabetes Interventions and Complications Study and the Michigan Bone Health and Metabolism Study. Fertil Steril 2016, 106(6):1446-52. PMC5159208.
  • Sandholm N, Van Zuydam N, Ahlqvist E, Juliusdottir T, Deshmukh HA, Rayner NW, Di Camillo B, Forsblom C, Fadista J, Ziemek D, Salem RM, Hiraki LT, Pezzolesi M, Trégouët D, Dahlström E, Valo E, Oskolkov N, Ladenvall C, Marcovecchio ML, Cooper J, Sambo F, Malovini A, Manfrini M, McKnight AJ, Lajer M, Harjutsalo V, Gordin D, Parkkonen M; FinnDiane Study Group, Tuomilehto J, Lyssenko V, McKeigue PM, Rich SS, Brosnan MJ, Fauman E, Bellazzi R, Rossing P, Hadjadj S, Krolewski A, Paterson AD; DCCT/EDIC Research Group, Florez JC, Hirschhorn JN, Maxwell AP; GENIE Consortium, Dunger D, Cobelli C, Colhoun HM, Groop L, McCarthy MI, Groop PH; SUMMIT Consortium. The genetic landscape of renal complications in type 1 diabetes. J Am Soc Nephrol 2016, Epub Sept.
  • Hotaling JM, Sarma AV, Patel DP, Braffett BH, Cleary PA, Feldman E, Herman WH, Martin CL, Jacobson AM, Wessells H, Pop-Busui R, the DCCT/EDIC Research Group. Cardiovascular autonomic neuropathy, sexual dysfunction, and urinary incontinence in women with type 1 diabetes. Diabetes Care 2016, 39(9):1587-93. PMCID:5001143.
  • Hammad SM, Baker NL, El Abiad JM, Spassieva SD, Pierce JS, Rembiesa B, Bielawski J, Lopes-Virella MF, Klein RL, the DCCT/EDIC Research Group. Increased plasma levels of select deoxy-ceramide and ceramide species are associated with increased odds of diabetic neuropathy in type 1 diabetes: a pilot study. Neuromolecular Med 2016, Epub July.
  • The DCCT/EDIC Research Group (Writing Committee: Lachin JM, Bebu I, Nathan DM, Zinman B, Brillon D, Backlund JC, Cleary PA, Orchard TJ). Mortality in Type 1 Diabetes in the DCCT/EDIC Versus the General Population. Diabetes Care 2016, 39(8):1378-83. PMCID:4955932.
  • The DCCT/EDIC Research Group (Writing Committee: Braffett BH, Dagogo-Jack S, Larkin M, Sivitz W, Bebu I, Kolterman O, Genuth S, Lachin JM). Coprogression of Cardiovascular Risk Factors in Type 1 Diabetes During 30 Years of Follow-up in the DCCT/EDIC Study. Diabetes Care 2016, 39(9):1621-30. PMCID:5001148.
  • Orchard TJ, Backlund JC, Costacou T, Cleary P, Lopes-Virella M, Levy AP, Lachin JM, the DCCT/EDIC Research Group. Haptoglobin 2-2 genotype and the risk of coronary artery disease in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study (DCCT/EDIC). J Diabetes Complications 2016, 30(8):1577-1584. PMCID:5050105.
  • Grassi MA, Rao VR, Chen S, Cao D, Gao X, Cleary PA, Huang RS, Paterson AD, Natarajan R, Rehman J, Kern TS, the DCCT/EDIC Research Group. Lymphoblastoid cell lines as a tool to study inter-individual differences in the response to glucose. PLoS One 2016, 11(8):e0160504. PMCID:4979894.
  • Darabian S, Backlund JY, Cleary PA, Sheidaee N, Bebu I, Lachin JM, Budoff MJ, the DCCT/EDIC Research Group. Significance of epicardial and intrathoracic adipose tissue volume among type 1 diabetes patients in the DCCT/EDIC: a pilot study. PLoS One 2016, 11(7):e0159958. PMCID:4961378.
  • Chen Z, Miao F, Paterson AD, Lachin JM, Zhang L, Schones DE, Wu X, Wang J, Tompkins JD, Genuth S, Braffett BH, the DCCT/EDIC Research Group, Natarajan R. Epigenomic profiling reveals an association between persistence of DNA methylation and metabolic memory in the DCCT/EDIC type 1 diabetes cohort. Proc Natl Acad Sci 2016, 113(21):E3002-11. PMCID:4890596.
  • Lenherr SM, Clemens JQ, Braffett BH, Dunn RL, Cleary PA, Kim C, Herman W, Hotaling JM, Jacobson AM, Brown JS, Wessells H, Sarma AV, and the DCCT/EDIC Research Group. Glycemic control and risk of incident urinary incontinence in women with type 1 diabetes: results from the DCCT/EDIC study. Diabet Med 2016, 33(11):1528-35. PMCID:5045319.
  • Lenherr SM, Clemens JQ, Braffett BH, Cleary PA, Dunn RL, Hotaling JM, Jacobson AM, Kim C, Herman W, Brown JS, Wessells H, Sarma AV, and the DCCT/EDIC Research Group. Glycemic control and urinary tract infections in women with type 1 diabetes: results from the DCCT/EDIC. J Urol 2016, 196(4):1129-35. PMCID:5025347.
  • Soliman EZ, Backlund JY, Bebu I, Li Y, Zhang ZM, Cleary PA, Lachin JM, and the DCCT/EDIC Research Group. Progression of electrocardiographic abnormalities in type 1 diabetes during 16 years of follow-up: the Epidemiology of Diabetes Interventions and Complications Study. J Am Heart Assoc 2016, 5(3):e002882. PMCID:4943265.
  • The DCCT/EDIC Research Group (Writing Committee: Nathan DM, Bebu I, Braffett BH, Orchard TJ, Cowie CC, Lopes-Virella M, Schutta M, Lachin JM). Risk factors for cardiovascular disease in type 1 diabetes. Diabetes 2016, 65(5):1370-9. PMCID:4829209.
  • Sell DR, Sun W, Gao X, Strauch C, Lachin JM, Cleary PA, Genuth S, and the DCCT/EDIC Research Group. Skin collagen fluorophore LW-1 versus skin fluorescence as markers for the long-term progression of subclinical macrovascular disease in type 1 diabetes. Cardiovasc Diabetol 2016, 15(1):30. PMCID:4750185.
  • Jaffa MA, Lutrell D. Schmaier AH, Klein RL, Lopes-Virella M, Lutrell LM, Jaffa AA, and the DCCT/EDIC Research Group. Plasma prekallikrein is associated with carotid intima-media thickness in type 1 diabetes. Diabetes 2016, 65(2):498-502. PMCID:4747454.
  • Porta M, Toppila I, Sandholm N, Hosseini SM, Forsblom C, Hietala K, Borio L, Harjutsalo V, Klein BE, Paterson AD, DCCT/EDIC Research Group, Groop PH, FinnDiane Study Group. Variation in A3 and protection from microvascular damage in type 1 diabetes.  Diabetes 2015, 65(4):1022-30. PMCID:4806664.
  • Kim C, Dunn RL, Braffett BH, Cleary PA, Arends V, Steffes M, Lanham MS, Randolph JF, Wessells H, Wellons MF, Sarma AV, and the DCCT/EDIC Research Group. Ovarian reserve in women with type 1 diabetes in the Diabetes Control and Complications/Epidemiology of Diabetes Interventions and Complications study. Diabet Med 2016, 35(5):691-2. PMCID:4837044.
  • The DCCT/EDIC Research Group (Writing Committee: Gubitosi-Klug R, Lachin JM, Backlund JYC, Lorenzi GM, Brillon DJ, Orchard TJ). Intensive diabetes treatment and cardiovascular outcomes in type 1 diabetes: the DCCT/EDIC study 30-year follow-up. Diabetes Care 2016, 39(5):686-93. PMCID:4839174.
  • Teumer A, Tin A, Sorice R, Gorski M, Yeo NC, Chu AY, Li M, Li Y, Mijatovic V, Ko YA, Taliun D, Luciani A, Chen MH, Yang Q, Foster MC, Olden M, Hiraki LT, Tayo BO, Fuchsberger C, Dieffenbach AK, Shuldiner AR, Smith AV, Zappa AM, Lupo A, Kollerits B, Ponte B, Stengel B, Krämer BK, Paulweber B, Mitchell BD, Hayward C, Helmer C, Meisinger C, Gieger C, Shaffer CM, Müller C, Langenberg C, Ackermann D, Siscovick D; DCCT/EDIC Research Group, et al. Genome-wide association studies identify genetic loci associated with albuminuria in diabetes. Diabetes 2015, 65(3):803-17. PMCID:4764151.
  • Zhang Y, Jenkins AJ, Basu A, Stoner JA, Lopes-Virella MF, Klein RL, DCCT/EDIC Research Group, Lyons TJ. Associations between intensive diabetes therapy and NMR-determined lipoprotein subclass profiles in type 1 diabetes. J Lipid Res 2016, 57(2):310-7. PMCID:4727426.
  • Kim C, Bebu I, Braffett B, Cleary PA, Arends V, Steffes M, Wessells H, Orchard T, Sarma AV, and the DCCT/EDIC Research Group. Testosterone and cardiac mass and function in men with type 1 diabetes in the Epidemiology of Diabetes Interventions and Complications Study (EDIC). Clin Endocrinol 2015, 84(5):693-9. PMCID:4824167.
  • Basu A, Jenkins AJ, Zhang Y, Stoner JA, Klein RL, Lopes-Virella MF, Garvey WT, Lyons TJ, and the DCCT/EDIC Research Group. Nuclear magnetic resonance-determined lipoprotein subclasses and carotid intima-media thickness in type 1 diabetes. Atherosclerosis 2015, 244:93-100. PMCID:4823999.
  • Kim C, Pop-Busui, Braffett BH, Cleary PA, Bebu I, Wessells H, Orchard T, Sarma AV, and the DCCT/EDIC Research Group. Testosterone concentrations and cardiovascular autonomic neuropathy in men with type 1 diabetes in the Epidemiology of Diabetes Interventions and Complications study (EDIC). J Sex Med 2015, 12(11):2153-9. PMCID:4825316.
  • Gubitosi-Klug RA, Sun W, Cleary PA, Braffett BH, Aiello AP, Das A, Tamborlane W, Klein R, and the DCCT/EDIC Research Group. Effects of prior intensive insulin therapy and risk factors on patient-reported visual function outcomes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) cohort. JAMA Ophthalmol 2015, 134(2):137-45. PMCID:4825807.
  • Lorenzi G, Braffett BH, Arends VL, Danis RP, Diminick L, Klumpp KA, Morrison AD, Soliman EZ, Steffes MW, Cleary PA, and the DCCT/EDIC Research Group. Quality control measures over 30 years in a multicenter clinical study: results from the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study. PLoS One 2015, 10(11):e0141286. PMCID:4631458.
  • Monnier VM, Sun W, Gao X, Sell DR, Cleary PA, Lachin JM, Genuth S, and the DCCT/EDIC Research Group. Skin collagen advanced glycation endproducts (AGEs) and the long-term progression of sub-clinical cardiovascular disease in type 1 diabetes. Cardiovasc Diabetol 2015, 14:118. PMCID:4560872.
  • Eny KM, Orchard TJ, Miller RG, Maynard J, Grant DM, Costacou T, Cleary PA, Braffett BH, the DCCT/EDIC Research Group, and Paterson AD. Caffeine consumption contributes to skin intrinsic fluorescence in type 1 diabetes. Diabetes Technol Ther 2015, 17(10):726-34. PMCID:4575521.
  • Jacobson AM, Braffett BH, Cleary PA, Dunn RL, Larkin ME, Wessells H, Sarma AV, and the DCCT/EDIC Research Group. The relationship of urologic complications to health-related quality of life and perceived value of health in men and women with type 1 diabetes: The Diabetes Control and Complications Trial/Epidemiology of Interventions and Complications (DCCT/EDIC) cohort. Diabetes Care 2015, 38(10):1904-12. PMCID:4580606.
  • Bharucha AE, Batey-Schaefer B, Cleary PA, Murray JA, Cowie C, Lorenzi G, Driscoll M, Harth J, Larkin M, Christofi M, Bayless M, Wimmergren N, Herman W, Whitehouse F, Jones K, Kruger D, Martin C, Ziegler G, Zinsmeister AR, Nathan DM, and the DCCT/EDIC Research Group. Delayed gastric emptying is associated with early and long-term hyperglycemia in type 1 diabetes mellitus. Gastroenterology 2015, 149(2):330-9. PMCID:4516593.
  • The DCCT/EDIC Research Group (Writing Committee: Aiello LP, Sun W, Das A, Gangaputra S, Kiss S, Klein R, Cleary PA, Lachin JM, Nathan DM). Intensive diabetes therapy and ocular surgery in type 1 diabetes. N Engl J Med 2015, 372(18):1722-33. PMCID:4465212.
  • Pop-Busui R, Hotaling J, Braffett BH, Cleary PA, Dunn RL, Martin CL, Jacobson AM, Wessells H, Sarma AV, and the DCCT/EDIC Research Group. Cardiovascular autonomic neuropathy, erectile dysfunction and lower urinary tract symptoms in men with type 1 diabetes: findings from the DCCT/EDIC. J Urol 2015, 193(6):2045-51. PMCID:4439436.
  • The DCCT/EDIC Research Group (Writing Committee: Orchard TJ, Nathan DM, Zinman B, Cleary P, Brillon D, Backlund JC, Lachin JM). Association between 7 years of intensive treatment of type 1 diabetes and long-term mortality. JAMA 2015, 313(1):45-53. PMCID:4306335.
  • Rajab HA, Baker NL, Hunt KJ, Klein R, Cleary PA, Lachin J, Virella G, Lopes-Virella MF, and the DCCT/EDIC Research Group. The predictive role of markers on inflammation and endothelial dysfunction on the course of diabetic retinopathy in type 1 diabetes. J Diabetes Complications 2015, 29(1):108-14. PMCID:4426877.
  • Hosseini SM, Boright AP, Sun L, Canty AJ, Bull SB, Klein BE, Klein R, the DCCT/EDIC Research Group, and Paterson AD. The association of previously reported polymorphisms for microvascular complications in a meta-analysis of diabetic retinopathy. Hum Genet 2015, 134(2):247-57. PMCID:4291513.
  • Basu A, Jenkins AJ, Stoner JA, Thorpe SR, Klein RL, Lopes-Virella MF, Garvey WT, Lyons TJ, and the DCCT/EDIC Research Group. Plasma total homocysteine and carotid-intima-media thickness in type 1 diabetes: a prospective study. Atherosclerosis 2014, 236(1):188-95. PMCID:4134979.
  • de Boer IH, Afkarian M, Rue TC, Cleary PA, Lachin JM, Molitch ME, Steffes MW, Sun W, Zinman B, and the DCCT/EDIC Research Group. Renal outcomes in patients with type 1 diabetes and macroalbuminuria. J Am Soc Nephrol 2014, 25(10):2342-50. PMCID:4178441.
  • The DCCT/EDIC Research Group (Writing Committee: Lachin JM, White N, Sun W, Cleary PA, Nathan D). Effect of intensive diabetes therapy on the progression of diabetes retinopathy in patients with type 1 diabetes: 18 years of follow-up in the DCCT/EDIC. Diabetes 2015, 64(2):631-42. PMCID:4303965.
  • Simpson CL, Wojciechowski R, Oexle K, Murgia F, Portas L, Li X, Verhoeven VJ, Vitart V, Schache M, Hosseini SM, Hysi PG, Raffel LJ, Cotch MF, Chew E, Klein BE, Klein R, Wong TY, van Duijn CM, Mitchell P, Saw SM, Fossarello M, Wang JJ; DCCT/EDIC Research Group, Polašek O, Campbell H, Rudan I, Oostra BA, Uitterlinden AG, Hofman A, Rivadeneira F, Amin N, Karssen LC, Vingerling JR, Döring A, Bettecken T, Bencic G, Gieger C, Wichmann HE, Wilson JF, Venturini C, Fleck B, Cumberland PM, Rahi JS, Hammond CJ, Hayward C, Wright AF, Paterson AD, Baird PN, Klaver CC, Rotter JI, Pirastu M, Meitinger T, Bailey-Wilson JE, Stambolian D. Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 Loci. PLoS One 2014, 9(9):e107110. PMCID:4169415.
  • Genuth S, Sun W, Cleary P, Gao X, Sell DR, Lachin J, and the DCCT/EDIC Research Group. Skin advanced glycation endproducts (AGEs) glucosepane and methyglyoxal hydroimidazolone are independently associated with long-term microvascular complication progress of type 1 diabetes. Diabetes 2015, 64(1):266-78. PMCID:4274803.
  • Sarma AV, Hotaling J, Dunn RL, Cleary PA, Braffett BH, Kim C, Martin C, Herman W, Gatcomb P, Jacobson AM, Holt S, Wessells H and the DCCT/EDIC Research Group. Poor glycemic control is associated with reduced prostate-specific antigen concentrations in men with type 1 diabetes. J Urol 2014, 193(3):766-93. PMCID:4363040.
  • McGee P, Steffes M, Nowicki M, Bayless M, Gubitosi-Klug R, Cleary P, Lachin J, Palmer J, and the DCCT/EDIC Research Group. Insulin secretion measured by stimulated C-peptide in long-established type 1 diabetes in the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) cohort: a pilot study. Diabet Med 2014, 31(10):1264-8. PMCID:4167980.
  • Arking DE, et al. Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nat Genet 2014, 46(8):826-36. PMCID:4124521.
  • The DCCT/EDIC Research Group (Writing Committee: de Boer IH, Sun W, Gao X, Cleary PA, Lachin JM, Molitch M, Steffes MW, Zinman B).  Effect of intensive diabetes treatment on albuminuria in type 1 diabetes: long-term follow-up of the Diabetes Control and Complications Trial and Epidemiology of Diabetes Interventions and Complications study. Lancet Diabetes Endocrinol 2014, 2(10):793-800. PMC4215637.
  • Holt SK, Lopushnyan N, Hotaling J, Sarma AV, Dunn RL, Cleary PA, Braffett BH, Gatcomb P, Martin C, Herman WH, Wessells H, The DCCT/EDIC Research Group. Prevalence of low testosterone and predisposing risk factors in men with type 1 diabetes mellitus: findings from the DCCT/EDIC. J Clin Endocrinol Metab. 2014, 99(9):E1655-60. PMCID:4154094.
  • Eny KM, Lutgers HL, Maynard J, Klein BE, Lee KE, Atzmon G, Monnier VM, van Vliet-Ostaptchouk JV, Graaff R, van der Harst P, Snieder H, van der Klauw MM, Sell DR, Hosseini SM, Cleary PA, Braffett BH, Orchard TJ, Lyons TJ, Howard K, Klein R, Crandall JP, Barzilai N, Milman S, Ben-Avraham D; LifeLines Cohort Study Group; DCCT/EDIC Research Group, Wolffenbuttel BH, Paterson AD. GWAS identifies an NAT2 acetylator status tag single nucleotide polymorphism to be a major locus for skin fluorescence. Diabetologia 2014, 57(8):1623-34. PMCID:4079945.
  • Miao F, Chen Z, Genuth S, Paterson AD, Zhang L, Wu X , Li SM,  Cleary P, Riggs A, Harlan DM, Lorenzi G, Kolterman O, Sun W, Lachin JM, Natarajan R, and the DCCT/EDIC Research Group.  Evaluating the role of epigenetic histone modifications in the Metabolic Memory of Type 1 Diabetes.  Diabetes 2014, 63(5):1748-62. PMCID:3994951.
  • Larkin ME, Barnie A, Braffett BH, Cleary PA, Diminick L, Harth J, Gatcomb P, Golden E, Lipps J, Lorenzi G, Mahony C, Nathan DM, and The DCCT/EDIC Research Group. Musculoskeletal Complications in Type 1 Diabetes. Diabetes Care 2014, 37(7):1863-9. PMCID:40667398.
  • The DCCT/EDIC Research Group (Writing Committee: Nathan DM). The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study at 30 years: Overview. Diabetes Care 2014, 37(1):9-16. PMC3867989.
  • Aiello LP, for the DCCT/EDIC Research Group. Diabetic retinopathy and other ocular findings in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications [DCCT/EDIC] study. Diabetes Care 2014, 37(1):17-23. PMCID:3867989.
  • de Boer IH, for the DCCT/EDIC Research Group. Renal disease and related findings in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study. Diabetes Care 2014, 37(1):24-30. PMCID:3867994.
  • Martin CL, Albers JW, Pop-Busui R, for the DCCT/EDIC Research Group. Neuropathy and related findings in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study. Diabetes Care 2014, 37(1):31-38. PMCID:3868000.
  • Lachin JM, Orchard TJ, Nathan DM, for the DCCT/EDIC Research Group. Update on cardiovascular outcomes at 30 years of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study. Diabetes Care 2014, 37(1):39-43. PMCID:3868002.
  • Gubitosi-Klug RA, for the DCCT/EDIC Research Group. The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study at 30 years: Summary and future directions. Diabetes Care 2014, 37(1):44-49. PMCID:3867991.
  • Lachin JM, McGee P, Palmer JP, for the DCCT/EDIC Research Group. Impact of c-peptide preservation on metabolic and clinical outcomes in The Diabetes Control and Complications Trial. Diabetes 2014, 63(2):739-748. PMCID:3900540.
  • Nathan DM, McGee P, Steffes MW, Lachin JM, and the DCCT/EDIC Research Group. Relationship of glycated albumin to blood glucose and glycated hemoglobin (HbA1c) values and to retinopathy, nephropathy and cardiovascular outcomes in the DCCT/EDIC study. Diabetes 2014, 63(1):282-290. PMCID:3868040.
  • Kim C, Cleary P, Cowie C, BraffettB, DunnR, Larkin M, Gatcomb P, Wessells H, Nathan D, Sarma A, and the DCCT/EDIC Research Group. Effect of glycemic treatment and microvascular complications on menopause in women with type 1 diabetes in the Diabetes Control and Complications/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) cohort. Diabetes Care 2014, 37(3):701-708. PMCID:3931380.
  • Buschur E, Sarma A, Pietropaolo M, Dunn R, Braffett BH, Cleary PA, Cowie C, Larkin ME, Wessells H, Nathan DM, Kim C, and the DCCT/EDIC Research Group. Self-reported autoimmune disease by gender in the Diabetes Control and Complications/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study. Diabetes Care 2014, 37(2):e28-29. PMCID:3898756.
  • The DCCT/EDIC Research Group (Writing Committee: de Boer IH, Sun W, Cleary PA, Lachin JM, Molitch ME, Zinman B, Steffes MW). Longitudinal changes in estimated and measured GFR in type 1 diabetes. J Am Soc Nephrol 2014, 25(4):810-818. PMC3968500.
  • The DCCT/EDIC Research Group (Writing Committee: Nathan DM, Bayless M, Cleary PA, Genuth S, Gubitosi-Klug R, Lachin JM, Lorenzi G, Zinman B). Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study at 30 years. Diabetes 2013, 62(12):3976-3786. PMC3837056.
  • Hunt K, Baker N, Cleary P, Backlund JY, Lyons T, Jenkins A, Virella G, Lopes-Virella M, and the DCCT/EDIC Research Group. Oxidized LDL and AGE-LDL in circulating immune complexes strongly predict progression of carotid artery IMT in type 1 diabetes. Atherosclerosis 2013, 231(2):315-322. PMCID:3924569.
  • Jenkins AJ, Yu J, Alaupovic F, Basu A, Klein RL, Lopes-Virella M, Baker NL, Hunt KJ, Lackland DT, Garvey WT, Lyons TJ, and the DCCT/EDIC Research Group. Apolipoprotein-defined lipoproteins and apolipoproteins: Associations with abnormal albuminuria in type 1 diabetes in the Diabetes Control and Complications/Epidemiology of Diabetes Interventions and Complications cohort. J Diabetes Complications 2013, 27(5):447-453. PMCID:4064461.
  • Jacobson AM, Braffett BH, Cleary PA, Gubitosi-Klug RA, Larkin ME, and the DCCT/EDIC Research Group. The long-term effects of type 1 diabetes treatment and complications on health-related quality of life: A 23-year follow-up of the Diabetes Control and Complications/Epidemiology of Diabetes Interventions and Complications cohort. Diabetes Care 2013, 36(10):3131-3138. PMCID:3781542.
  • Grassi MA, Sun W, Gangaputra S, Cleary PA, Hubbard L, Lachin JM, Gao X, Kiss S, Backmeier AJ, Almony A, Davis M, Klein R, Danis R, for the DCCT/EDIC Research Group.  Validity of self-report in type 1 diabetic subjects for laser treatment of retinopathy.  Ophthalmology 2013, 120(12):2580-2586. PMCID:3818390.
  • Orchard T, Lyons TJ, Cleary PA, Braffett BH, Maynard J, Cowie C, Gubitosi-Klug R, Anderson K, Barnie A, Villavicencio S, and the DCCT/EDIC Research Group.  The association of skin intrinsic fluorescence with type 1 diabetes complications in the DCCT/EDIC study.  Diabetes Care 2013, 36(10):3146-3153. PMCID:3781515.
  • Cheng CY, et al. Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. Am J Hum Genet 2013, 93(2):264-277. PMCID:3772747.
  • Orchard T, Sun W, Cleary P, Genuth S, Lachin J, McGee P, Paterson A, Raskin P, Anbinder Y, Levy A, and the DCCT/EDIC Research Group.  Haptoglobin genotype and the rate of renal function decline in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study.  Diabetes 2013, 62(9):3218-3223. PMCID:3749329.
  • Cleary PA, Braffett BH, Orchard T, Lyons TJ, Maynard J, Cowie C, Gubitosi-Klug RA, Way J, Anderson K, Barnie A, Villavicencio S, and the DCCT/EDIC Research Group. Clinical and technical factors associated with skin intrinsic fluorescence in subjects with type 1 diabetes from the DCCT/EDIC study. Diabetes Technol Ther 2013, 15(6):466-474. PMCID:4428254.
  • Stambolian D, Wojciechowski R, Oexle K, Pirastu M, Li X, Raffel L, Cotch MF, Chew E, Klein B, Klein R, Wong T, Simpson CL, Klaver C, van Duijn C, Verhoeven V, Baird P, Vitart V, Paterson A, Mitchell P, Saw SM, Fossarello M, Kazmierkiewicz K, Murgia F, Portas L, Schache M, Richardson A, Xie J, Wang JJ, Rochtchina E, DCCT/EDIC Research Group, Viswanathan A, Hayward C, Wright A, Polašek O, Campbell H, Rudan I, Oostra B, Uitterlinden A, Hofman A, Rivadeneira F, Amin N, Karssen L, Vingerling J, Hosseini SM, Döring A, Bettecken T, Vatavuk Z, Gieger C, Wichmann H-E, Wilson J, Fleck B, Foster P, Topouzis F, McGuffin P, Sim X, Inouye M, Holliday E, Attia J, Scott R, Rotter J, Meitinger T, Bailey-Wilson J.  Meta-analyses of genome-wide association studies in 5 cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error.  Hum Mol Genet 2013, 22(13):2754-2764. PMCID:3674806.
  • Sachs MC, Brunzell JD, Cleary PA, Hoofnagle AN, Lachin JM, Molitch ME, Steffes MW, Zinman B, de Boer IH, and the DCCT/EDIC Research Group. Circulating vitamin D metabolites and subclinical atherosclerosis in type 1 diabetes. Diabetes Care 2013, 36(8):2423-2429. PMCID:3714470.
  • Genuth S, Backlund JYC, Bayless M, Bluemke DA, Cleary PA, Crandall J, Lachin JM, Lima JAC, Miao C, Turkbey EB, and the DCCT/EDIC Research Group.  Effects of prior intensive versus conventional therapy and history of glycemia on cardiac function in type 1 diabetes in the DCCT/EDIC. Diabetes 2013, 62(10):3561-3569. PMCID:3781466.
  • Lopes-Virella MF, Baker NL, Hunt KJ, Cleary PA, Klein R, Virella G, and the DCCT/EDIC Research Group.  Baseline markers of inflammation are associated with progression to macroalbuminuria in type 1 diabetic subjects.  Diabetes Care 2013, 36(8):2317-2323. PMCID:3714479.
  • Turkbey EB, Redheuil A, Backlund JY, Small AC, Cleary PA, Lachin JM, Lima JAC, Bluemke DA, and the DCCT/EDIC Research Group. Aortic distensibility in type 1 diabetes. Diabetes Care 2013, 36(8):2380-2387. PMCID:3714531.
  • Verhoeven VJM, Hysi PG, Wojciechowski R, Qiao Q, Guggenheim JA, Höhn R, MacGregor S, Hewitt AW, Nag A, Cheng C-Y, Yonova-Doing E, Zhou X, Ikram, MK, Buitendijk GHS, McMahon G, Kemp JP, St. Pourcain B, Simpson CL, Mäkelä K-M, Lehtimäki T, Kähönen M, Paterson AD, Hosseini SM, Wong HS, Xu L, Jonas JB, Pärssinen O, Wedenoja J, Yip SP, Ho DWH, Pang CP, Chen LJ, Burdon KP, Craig JE, Klein BEK, Klein R, Haller T, Metspalu A, Khor C-C, Tai ES, Aung T, Vithana E, Tay W-T, Barathi VA, the CREAM Consortium, Chen P, Li R, Liao J, Zheng Y, Ong RT, Döring A, DCCT/EDIC Research Group, Evans DM, Timpson NJ, Verkerk AJMH, Meitinger T, Raitakari O, Hawthorne F, Spector TD, Karssen LC, Pirastu M, Murgia F, Ang W, Wellcome Trust Case Control Consortium 2, Mishra A, Montgomery GW, Pennell CE, Cumberland PM, Cotlarciuc I, Mitchell P, Wang JJ,  Schache M, Janmahasathian S, Igo Jr, RP, Lass JH, Chew E, Iyengar SK, the Fuchs' Genetics Multi-Center Study Group, Gorgels TGMF, Rudan I, Hayward C, Wright AF, Polasek O, Vatavuk Z, Wilson JF, Fleck B, Zeller T, Mirshahi A, Müller C, Uitterlinden AG, Rivadeneira F, Vingerling JR, Hofman A, Oostra BA, Amin N, Bergen AAB, Teo Y-Y, Rahi JS, Vitart V, Williams C, Baird PN, Wong T-Y, Oexle K, Pfeiffer N, Mackey DA, Young TL, van Duijn CM, Saw S-M, Bailey Wilson JE, Stambolian D, Klaver CC, Hammond CJ. The Genome-wide meta-analyses of multi-ethnic cohorts identify multiple new susceptibility loci for refractive error and myopia.  Nat Genet 2013, 45(3):314-318. PMCID:3740568.
  • Purnell JQ, Hokanson JE, Cleary PA, Nathan DM, Lachin JM, Zinman B, Brunzell JD, and the DCCT/EDIC Research Group. The effect of excess weight gain with intensive diabetes treatment on cardiovascular disease risk factors and atherosclerosis in type 1 diabetes mellitus: Results from the Diabetes Control and Complications Trial / Epidemiology of Diabetes Interventions and Complications Study (DCCT/EDIC). Circulation 2013, 127(2):180-187. PMCID:3819101.
  • Pop-Busui R, Cleary PA, Braffett BH, Martin CL, Herman WH, Low PA, Lima JAC, Bluemke DA, and the DCCT/EDIC Research Group. Association between cardiovascular autonomic neuropathy and left ventricular dysfunction in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study. J Am Coll Cardiol 2013, 61(4):447-454. PMCID:3616477.
  • Monnier VM, Sell DR, Strauch C, Sun W, Lachin JM, Cleary PA, Genuth S, and the DCCT/EDIC Research Group. The association between skin collagen glucosepane and past progression of microvascular and neuropathic complications in type 1 diabetes. J Diabetes Complications 2013, 27(2):141-149. PMCID:3577949.
  • Kramer JR, Bayless ML, Lorenzi GM, Ziegler GK, Larkin ME, Lackaye ME, Harth J, Diminick LJ, Klumpp KA, Bourne PA, Anderson KL, Braffett BH, Cleary PA, and the DCCT/EDIC Research Group. Participant characteristics and study features associated with high retention rates in a longitudinal investigation of type1 diabetes mellitus. Clin Trials 2012, 9(6):798-805. PMCID:3762976.
  • de Boer IH, Sachs MC, Cleary PA, Hoofnagle AN, Lachin JM, Molitch ME, Steffes MW, Sun W, Zinman B, Brunzell JD, and the DCCT/EDIC Research Group. Circulating vitamin D metabolites and kidney disease in type 1 diabetes. J Clin Endocrinol Metab 2012, 97(12): 4780-4788. PMCID:3513544.
  • Chahal H, Backlund JYC, Cleary PA, Lachin JM, Polak J, Lima JAC, Bluemke DA, and the DCCT/EDIC Research Group. Relationship between carotid intima-media thickness and left ventricular mass in type 1 diabetes mellitus (from the Epidemiology of Diabetes Interventions and Complications [EDIC] study). Am J Cardiol 2012, 110(10): 1534-1540. PMCID:3488435.
  • Sandholm N, Salem RM, McKnight AJ, Brennan EP, Forsblom C, Isakova T, McKay GJ, Williams WW, Sadlier DM, Mäkinen VP, Swan EJ, Palmer C, Boright AP, Ahlqvist E, Deshmukh HA, Keller BJ, Huang H, Ahola AJ, Fagerholm E, Gordin D, Harjutsalo V, He B, Heikkilä O, Hietala K, Kytö J, Lahermo P, Lehto M, Lithovius R, Osterholm AM, Parkkonen M, Pitkäniemi J, Rosengård-Bärlund M, Saraheimo M, Sarti C, Söderlund J, Soro-Paavonen A, Syreeni A, Thorn LM, Tikkanen H, Tolonen N, Tryggvason K, Tuomilehto J, Wadén J, Gill GV, Prior S, Guiducci C, Mirel DB, Taylor A, Hosseini SM; DCCT/EDIC Research Group, Parving HH, Rossing P, Tarnow L, Ladenvall C, Alhenc-Gelas F, Lefebvre P, Rigalleau V, Roussel R, Tregouet DA, Maestroni A, Maestroni S, Falhammar H, Gu T, Möllsten A, Cimponeriu D, Ioana M, Mota M, Mota E, Serafinceanu C, Stavarachi M, Hanson RL, Nelson RG, Kretzler M, Colhoun HM, Panduru NM, Gu HF, Brismar K, Zerbini G, Hadjadj S, Marre M, Groop L, Lajer M, Bull SB, Waggott D, Paterson AD, Savage DA, Bain SC, Martin F, Hirschhorn JN, Godson C, Florez JC, Groop PH, Maxwell AP. New susceptibility loci associated with kidney disease in type 1 diabetes. PLoS Genet 2012, 8(9): e1002921. PMCID:3447939.
  • Hotaling JM, Waggott DR, Goldberg J, Jarvik G, Paterson AD, Cleary PA, Lachin J, Sarma A, Wessells H, and the DCCT/EDIC Research Group. Pilot genome-wide association search identifies potential loci for risk of erectile dysfunction in type 1 diabetes using the DCCT/EDIC study cohort. J Urol 2012, 188(2):514-520. PMCID:3764461.
  • Larkin ME, Lorenzi GM, Bayless M, Cleary PA, Barnie A, Golden E, Hitt S, Genuth S, and the DCCT/EDIC Research Group. Evolution of the Study Coordinator Role: The 28 year experience of the DCCT/EDIC. Clin Trials 2012, 9(4):418-425. PMCID:3815574.
  • Herman WH, Pop-Busui R, Braffett BH, Martin CL, Cleary PA, Albers JW, Feldman EL, and the DCCT/EDIC Research Group. Use of the Michigan Neuropathy Screening Instrument as a measure of distal symmetrical peripheral neuropathy in Type 1 diabetes: Results from the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC).  Diabet Med 2012, 29(7):937-944. PMCID:3641573.
  • van Koolwijk LME, Ramdas WD, Ikram MK, Jansonius NM, Pasutto F, Hysi PG, Macgregor S, Janssen SF, Hewitt AW, Viswanathan AC, Ten Brink JB, Hosseini SM, Amin N, Despriet DD, Willemse-Assink JJ, Kramer R, Rivadeneira F, Struchalin M, Aulchenko YS, Weisschuh N, Zenkel M, Mardin CY, Gramer E, Welge-Lüssen U, Montgomery GW, Carbonaro F, Young TL, DCCT/EDIC Research Group, Bellenguez C, McGuffin P, Foster PJ, Topouzis F, Mitchell P, Wang JJ, Wong TY, Czudowska MA, Hofman A, Uitterlinden AG, Wolfs RC, de Jong PT, Oostra BA, Paterson AD, Wellcome Trust Case Control Consortium 2, Mackey DA, Bergen AA, Reis A, Hammond CJ, Vingerling JR, Lemij HG, Klaver CC, van Duijn CM. Common genetic determinants of intraocular pressure and primary open-angle glaucoma.  PLoS Genet 2012, 8(5):e1002611. PMCID:3342933.
  • Lopes-Virella MF, Baker NL, Hunt KJ, Lyons TJ, Jenkins AJ, Virella G, and the DCCT/EDIC Research Group.  High concentrations of AGE-LDL and oxidized LDL in circulating immune complexes are associated with progression of retinopathy in type 1 diabetes. Diabetes Care 2012, 35(6):1333-1340. PMCID:3357232.
  • Lopes-Virella MF, Carter RE, Baker NL, Lachin J, Virella G, and the DCCT/EDIC Research Group. High levels of oxidized LDL in circulating immune complexes are associated with increased odds of developing abnormal albuminuria in Type 1 diabetes. Nephrol Dial Transplant 2012, 27(4):1416-1423. PMCID:3471550.
  • The DCCT/EDIC Research Group (Writing Committee: de Boer IH, Sun W, Cleary PA, Lachin JL, Molitch ME, Steffes MW, Zinman B). Intensive diabetes therapy and glomerular filtration rate in type 1 diabetes.  N Engl J Med 2011, 365(25):2366-2376. PMCID:3270008.
  • Turkbey EB, Backlund JYC, Genuth S, Jain A, Miao C, Cleary PA, Lachin JM, Nathan DM, van der Geest RJ, Soliman EZ, Liu CY, Lima JAC, Bluemke DA, and the DCCT/EDIC Research Group.  Myocardial structure, function and scar in patients with type 1 diabetes. Circulation 2011, 124(16):1737-1746.  PMCID:3215589.
  • Hubbard LD, Sun W, Cleary PA, Danis RP, Hainsworth DP, Peng Q, Susman RA, Aiello LP, Davis MD, and the DCCT/EDIC Research Group. Comparison of digital and film grading of diabetic retinopathy severity in the DCCT/EDIC study.  Arch Ophthalmol 2011, 129(6):718-726. PMID:21670338.
  • Gai N, Turkbey EB, Nazarian S, van der Geest RJ, Liu CY, Lima JA, Bluemke DA. T(1) Mapping of the gadolinium-enchanced myocardium: Adjustment for factors affecting interpatient comparison.  Magn Reson Med, 2011, 65(5):1407-1415. PMCID:3092826.
  • Wessells H, Penson DF, Cleary P, Rutledge BN, Lachin JM, McVary KT, Schade DS, Sarma AV, and the DCCT/EDIC Research Group.  Effect of intensive glycemic therapy on erectile function in men with type 1 diabetes.  J Urol 2011, 185(5):1828-1834. PMCID:3220602.
  • de Boer IH, Paterson AD, Brunzell JD.  Reply to letter to editor, ‘Long-term renal outcomes of patients with type 1 diabetes and microalbuminuria: An analysis of the DCCT/EDIC cohort'. Arch Intern Med 2011, 171(5):1597. PMID:21949179.
  • de Boer IH, Rue TC, Cleary PA, Lachin JM, Molitch ME, Steffes MW, Sun W, Zinman B, Brunzell JD, and the DCCT/EDIC Research Group. Long-term renal outcomes of patients with type 1 diabetes and microalbuminuria:  An analysis of the DCCT/EDIC cohort. Arch Intern Med 2011,171(5):412-420. PMCID:3085024.
  • Nathan DM, Steffes MW, Sun W, Rynders GP, Lachin JM.  Determining stability of stored samples retrospectively: The validation of glycated albumin. Clin Chem 2011, 57(2):286-290.  PMID:21030684.
  • Sacks DB, Nathan DM, Lachin JM.  Gaps in the glycation gap hypothesis. Clin Chem 2011, 57(2):150-152.  PMID:21127149.
  • Jacobson, AM, Ryan CM, Cleary PA, Waberski BH, Weinger K, Musen G, Dahms W, and the DCCT/EDIC Research Group. Biomedical risk factors for decreased cognitive functioning in type 1 diabetes: An 18 year follow-up of the DCCT cohort. Diabetologia 2011, 54(2):245-255. PMID:20803190.
  • Polak JF, Backlund JYC, Cleary PA, Harrington AP, O'Leary DH, Lachin JM, Nathan DM, and the DCCT/EDIC Research Group.  Progression of carotid artery intima-media thickness during 12 years in the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) study.  Diabetes 2011, 60(2):607-613. PMCID:3028362.
  • Sun L, Dimitromanolaki A, Faye LL, Paterson AD, Waggott D, DCCT/EDIC Research Group, Bull SB. BR-squared: A practical solution to the winner's curse in genome-wide scans. Hum Genet 2011, 129(5):545-552. PMCID:3074069.
  • Wang B, Carter RE, Jaffa MA, Nakerakanti S, Lackland D, Lopes-Virella M, Trojanowska M, Luttrell LM, Jaffa AA, and the DCCT/EDIC Research Group. Genetic variant in the promoter of connective tissue growth factor gene confers susceptibility to nephropathy in type 1 diabetes. J Med Genet. 2011, 47(6):391-397. PMCID:3828650.
  • Klein RL, Carter RE, Jenkins AJ, Lyons TJ, Baker NL, Gilbert GE, Virella G, Lopes-Virella MF, and the DCCT/EDIC Research Group. LDL-containing immune complexes in the DCCT/EDIC cohort: Associations with lipoprotein subclasses.  J Diabetes Complications 2011, 25(2):73-82. PMCID:2978771.
  • Lopes-Virella MF, Hunt KJ, Baker NL, Lachin J, Nathan DM, Virella G, and the DCCT/EDIC Research Group. Levels of oxidized LDL and advanced glycation end products-modified LDL in circulating immune complexes are strongly associated with increased levels of carotid intima-media thickness and its progression in type 1 diabetes. Diabetes 2011, 60 (2):582-589. PMCID:3028359.
  • Lopes-Virella MF, Baker NL, Hunt KJ, Lachin J, Nathan D, Virella G, and the DCCT/EDIC Research Group. Oxidized LDL Immune Complexes and Coronary Artery Calcification in Type 1 Diabetes. Atherosclerosis 2011, 214(2):462-467. PMCID:3031663.
  • Paterson AD, Waggott D, Boright AP, Hosseini SM, Shen E, Sylvestre MP, Wong I, Bharaj B, Cleary PA, Lachin JM, MAGIC, Below JE, Nicolae D, Cox NJ, Canty AJ, Sun L, Bull SB, and the DCCT/EDIC Research Group. A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose. Diabetes 2010, 59(2):539-549. PMCID:2809960.
  • Böger CA, Chen MH, Tin A, Olden M, Köttgen A, de Boer IH, Fuchsberger C, O'Seaghdha CM, Pattaro C, Teumer A, Liu CT, Glazer NL, Li M, O'Connell JR, Tanaka T, Peralta CA, Kutalik Z, Luan J, Zhao JH, Hwang SJ, Akylbekova E, Kramer H, van der Harst P, Smith AV, Lohman K, de Andrade M, Hayward C, Kollerits B, Tönjes A, Aspelund T, Ingelsson E, Eiriksdottir G, Launer LJ, Harris TB, Shuldiner AR, Mitchell BD, Arking DE, Franceschini N, Boerwinkle E, Egan J, Hernandez D, Reilly M, Townsend RR, Lumley T, Siscovick DS, Psaty BM, Kestenbaum B, Haritunians T, Bergmann S, Vollenweider P, Waeber G, Mooser V, Waterworth D, Johnson AD, Florez JC, Meigs JB, Lu X, Turner ST, Atkinson EJ, Leak TS, Aasarød K, Skorpen F, Syvänen AC, Illig T, Baumert J, Koenig W, Krämer BK, Devuyst O, Mychaleckyj JC, Minelli C, Bakker SJ, Kedenko L, Paulweber B, Coassin S, Endlich K, Kroemer HK, Biffar R, Stracke S, Völzke H, Stumvoll M, Mägi R, Campbell H, Vitart V, Hastie ND, Gudnason V, Kardia SL, Liu Y, Polasek O, Curhan G, Kronenberg F, Prokopenko I, Rudan I, Arnlöv J, Hallan S, Navis G; the CKDGen Consortium, Parsa A, Ferrucci L, Coresh J, Shlipak MG, Bull SB, Paterson AD; DCCT/EDIC Research Group, Wichmann HE, Wareham NJ, Loos RJ, Rotter JI, Pramstaller PP, Cupples LA, Beckmann JS, Yang Q, Heid IM, Rettig R, Dreisbach AW, Bochud M, Fox CS, Kao WH. CUBN is a gene locus for albuminuria. J Am Soc Nephrol 2010, 22 (3):555-570. PMCID:3060449.
  • Martin CL, Waberski BH, Pop-Busui R, Cleary PA, Catton S, Albers JW, Feldman EL, Herman WH, and the DCCT/EDIC Research Group.  Vibration perception threshold as a measure of distal symmetrical peripheral neuropathy in type 1 diabetes.  Diabetes Care 2010, 33(12):2635-2641. PMCID:2992204.
  • Jacobson AM, Ryan C, Cleary P, Waberski B, Weinger K, Musen G, Dahms W, Bayless M, Silvers N, Harth J, and the DCCT/EDIC Research Group. Biomedical risk factors for decreased cognitive functioning in type 1 diabetes: An 18 year follow-up of the DCCT cohort.  Diabetologia 2010, 54(2):245-255. PMID:20803190.
  • Pop-Busui R, Herman WH, Feldman EL, Low PA, Martin CL, Cleary PA, Waberski BH, Lachin JM, Albers JW, and the DCCT/EDIC Research Group. DCCT/EDIC Studies in Type 1 Diabetes:  Lessons for diabetic neuropathy regarding metabolic memory and natural history. Curr Diab Rep 2010, 10(4):276-282. PMCID:3608672.
  • Younes N, Cleary PA, Steffes MW, de Boer IH, Molitch ME, Rutledge BN, Lachin JM, Dahms W, and the DCCT/EDIC Research Group. Comparison of urinary albumin-creatinine ratio and albumin excretion rate in the DCCT/EDIC study. Clin J Am Soc Nephrol 2010, 5(7):1235-1242. PMCID:2893069.
  • Molitch M, Steffes M, Sun W, Rutledge B, Cleary P, de Boer IH, Zinman B, Lachin J, and the DCCT/EDIC Research Group. Development and progression of renal insufficiency with and without albuminuria in adults with type 1 diabetes mellitus in the DCCT/EDIC study. Diabetes Care 2010, 33(7):1536-1543. PMCID:2890355.
  • Kern EF, Erhard P, Sun W, Genuth S, Weiss MF, and the DCCT/EDIC Research Group. Early urinary markers of diabetic kidney disease: A nested case-control study from the DCCT.  Am J Kid Dis 2010, 55(5):824-834. PMCID:2864367.
  • White NH, Sun W, Cleary PA, Tamborlane WV, Danis RP, Hainsworth DP, Davis MD, and the DCCT/EDIC Research Group. Effect of prior intensive therapy in type 1 diabetes on 10-year progression of retinopathy in the DCCT/EDIC: Comparison of adults and adolescents. Diabetes 2010, 59(5):1244-1253. PMCID:2857905.
  • Albers JW, Herman WH, Feldman EL, Pop-Busui R, Martin CL, Cleary PA, Waberski BH, Lachin JM, and the DCCT/EDIC Research Group.  Effect of prior intensive insulin therapy on peripheral neuropathy in type 1 diabetes. Diabetes Care 2010, 33(5):1090-1096. PMCID:2858182.
  • Larkin ME, Backlund JC, Cleary PA, Bayless M, Schaefer BJ, Canady J, Nathan DM, and the DCCT/EDIC Research Group. Disparity in the management of Coronary Heart Disease (CHD) risk factors by sex in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) cohort.  Diabet Med 2010, 27(4):451-458. PMID: 20536518.
  • Yoo YJ, Bull SB, Paterson AD, Waggott D, DCCT/EDIC Research Group, Sun L, and the DCCT/EDIC Research Group. Were genome-wide linkage studies a waste of time? Exploiting candidate regions within genome-wide association studies. Genet Epidemiol 2010, 34(2):107-118. PMCID:2811772.
  • Jacobson AM, Paterson A, Ryan C, Cleary P, Waberski B, Weinger K, Musen G, Dahms W (past), Bayless M, Silvers N, Harth J, Boright A, and the DCCT/EDIC Research Group. The associations of apolipoprotein E and angiotensin converting enzyme polymorphisms and cognitive function in type 1 diabetes based on an 18 year follow-up of the DCCT cohort. Diabet Med 2010, 27(1):15-22. PMCID:3043372.

STATISTICAL METHODS

  • Lachin JM. Power of the Mantel-Haenszel and other tests for discrete or grouped time-to-event data under a chained binomial model. Stat Med 2013, 32:220-229. PMCID:3634579.
  • Lachin JM. Power and sample size evaluation for the Cochran-Mantel-Haenszel mean score (Wilcoxon rank sum) test and the Cochran-Armitage test for trend. Stat Med 2011, 30(25):3057-3066. PMID:22006667.